| 摘要 |
PROBLEM TO BE SOLVED: To provide large-scale bioreactors, large-scale bioreactor systems, and bioreactors and methods for large-scale cultivation and propagation of mammalian cells using these bioreactors.SOLUTION: A bioreactor 1 for cultivation of mammalian cells has a volume of at least 4000 L and at least one top impeller 68 and at least one bottom impeller 78. The top impeller 68 is a hydrofoil impeller. A top impeller power number (Np) is at least 0.1 and at most 0.9. |
