| 发明名称 |
Mycobacterium Antigenic Composition |
| 摘要 |
Immunogenic compositions comprising an Rv1196 related antigen, wherein the conductivity of the composition is 13 mS/cm or lower, or the concentration of salts of the composition is 130 mM or lower, and their use in medicine, are provided. |
| 申请公布号 |
US2016220656(A1) |
申请公布日期 |
2016.08.04 |
| 申请号 |
US201615131422 |
申请日期 |
2016.04.18 |
| 申请人 |
GlaxoSmithKline Biologicals, S.A. |
发明人 |
GODART Stephane Andre Georges;LAANAN Amina;LEMOINE Dominique Ingrid |
| 分类号 |
A61K39/04 |
主分类号 |
A61K39/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An immunogenic composition comprising an Rv1196 related antigen, said composition further comprising a polyol,
wherein the conductivity of said composition is 5 mS/cm or lower, wherein the osmolality of said composition is 250 to 750 mOsm/kg, wherein the pH of said composition is in the range 7.0 to 9.0, and wherein the Rv1196 related antigen comprises a sequence having at least 90% identity to SEQ ID No: 1; and wherein said immunogenic composition is pharmaceutically acceptable. |
| 地址 |
Rixensart BE |
