摘要 |
Provided is a method for producing synthetic amylospheroids efficiently, the method including agitating a liquid containing amyloid ²-peptides in the presence of a plasticizer. Amylospheroid refers to an assembly of amyloid ²-peptides that selectively can induce cell death of functionally mature neurons. Amylospheroid is considered to play a central role in the development of Alzheimer's disease and dementia with Lewy bodies. |