Methods of making and using antibodies directed to parathyroid hormone

摘要

The present invention relates to methods of generating anti-PTH antibodies and antibodies generated by the methods of the invention. The anti-PTH antibodies generated by the methods of the invention specifically bind to an epitope on a whole PTH (1-84) which includes one or more N-terminal amino acid residues of the whole PTH. The anti-PTH antibodies generated are useful for detecting whole PTH in a biological sample and for diagnosing parathyroid diseases or disorders.