Compositions and methods

摘要

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.

主权项

1. A method of treating or inhibiting a dysbiosis, comprising administering an effective amount of a composition consisting of a population of germinatable bacterial spores and a pharmaceutically acceptable excipient to a subject, wherein the effective amount of the composition administered to the subject populates the gastrointestinal tract in the subject and augments growth of at least one type of bacteria not detectably present in the composition or in the gastrointestinal tract prior to administration, thereby treating the dysbiosis, inhibiting the dysbiosis, or reducing a severity of at least one symptom of the dysbiosis in the subject.