Mutant IL-15 polyp eptides and compositions including the polypeptides are described herein. In various embodiments, a mutant IL-15 polypeptide is joined to a heterologous polypeptide. Also described herein are uses of the mutant IL-15 polypeptides, e.g., in suppressing immune responses.
申请公布号
WO2006020849(A3)
申请公布日期
2006.10.05
申请号
WO2005US28713
申请日期
2005.08.11
申请人
BETH ISRAEL DEACONESS MEDICAL CENTER, INC.;F. HOFFMANN-LA ROCHE AG;ZHENG, XIN, XIAO;STROM, TERRY, B.;MOLL, THOMAS