| 摘要 |
<p>The present invention provides a magnetic sensor device (20) for determining the presence and/or amount of target moieties (32) in a sample fluid, the target moieties being labeled with magnetic or magnetizable objects (33). The magnetic sensor device (20) comprises a sensor surface (23) lying in a plane, at least one magnetic element (21) for providing a sensor signal and at least one structure (24) extending from the sensor surface (23) in a direction substantially perpendicular to the plane of the sensor surface (23), the at least one structure (24) having a height (h) and a binding surface (25) for binding the labeled target moieties (32). The height (h) of the at least one structure (24) is higher than zero and lower or equal to a distance (z) of the labeled target moieties (32) from the sensor surface (23) corresponding to a signal cross-over point (27) from positive to negative signal contribution of the labeled target moieties (32) to the sensor signal, the signal cross-over point (27) being the distance at which a homogeneous distribution of magnetic or magnetizable objects (33) between the sensor surface (23) and that distance has a signal contribution to the sensor signal equal to zero.</p> |
