1-BENZYLPYRAZOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

摘要

The invention relates to compounds of the formula (I) in which: Y is a group selected from N(R7)CO-, -N(R7)CO-N(R7)-, -OCO-, -N(R7)S(O)n-; R1 is a hydrogen atom or a (C1-C4)alkyl group; R6 is a group selected from a (C1-C6)alkyl group, phenyl, benzyl or benzohydryl, a heterocyclic radical, a carbocyclic radical, a C3-C7)cycloalkylmethyl group; said salts being in state of a base or addition salts to an acid. The invention also relates to methods for preparing compounds of the formula (I) and to the use thereof as CB2 receptor antagonists that can cross the intestinal barrier for the treatment for autoimmune disorders, pain, gastrointestinal disorders, cardiovascular disorders and cancer.