发明名称 |
SOLID DISPERSION CONTAINING DUTASTERIDE, AND COMPOSITION CONTAINING SAME |
摘要 |
The present invention relates to a pharmaceutical composition containing dutasteride and a method for preparing same. More specifically, the solubility of a drug has been increased by preparing an inclusion complex from gamma-cyclodextrin which is good for solidification so as to prepare a solid formulation containing dutasteride and by preparing a solid dispersion from the inclusion complex and a thickener and/or a surfactant. The solid formulation for oral administration comprising the solid dispersion granules prepared according to the present invention has the same PK profile as an Avodart soft capsule. |
申请公布号 |
WO2016126058(A3) |
申请公布日期 |
2016.09.29 |
申请号 |
WO2016KR01035 |
申请日期 |
2016.01.29 |
申请人 |
WHANIN PHARMACEUTICAL. CO., LTD. |
发明人 |
AHN, Byung-Nak;MIN, Mi Hong;PARK, Jin Hyeong |
分类号 |
A61K47/40;A61K9/20;A61K31/58;A61K47/34 |
主分类号 |
A61K47/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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