发明名称 |
Enolase 1 (Eno1) compositions and uses thereof |
摘要 |
The invention provides compositions comprising Enol for delivery to a muscle. Further, the invention provides a method for normalizing blood glucose in a subject with elevated blood glucose, comprising administering to the subject enolase 1 (Enol), thereby normalizing blood glucose in the subject. The invention also provides methods of treating one or more conditions including impaired glucose tolerance, insulin resistance, pre-diabetes, and diabetes, especially type 2 diabetes in a subject, comprising administering to the subject enolase 1 (Enol), thereby treating the condition in the subject. In certain methods of the invention, the Enol is delivered to muscle. |
申请公布号 |
AU2015204452(A1) |
申请公布日期 |
2016.08.11 |
申请号 |
AU20150204452 |
申请日期 |
2015.01.13 |
申请人 |
UNIVERSITY OF MIAMI;BERG LLC |
发明人 |
NARAIN, NIVEN RAJIN;SARANGARAJAN, RANGAPRASAD;VISHNUDAS, VIVEK K.;GESTA, STEPHANE;JING, ENXUAN;DAUNERT, SYLVIA;DEO, SAPNA K.;JIMENEZ, JOAQUIN JUAN;DIKICI, EMRE;DAFTARIAN, PIROUZ MOHAMMAD |
分类号 |
A61K38/17;A61K38/46;A61P3/10 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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