发明名称 |
RETARGETED HERPESVIRUS WITH A GLYCOPROTEIN H FUSION |
摘要 |
The present invention relates to the field of disease therapy. More specifically, it relates to a retargeted herpesvirus having a heterologous polypeptide fused to glycoprotein H, wherein the polypeptide targets diseased cells. It also relates to a nucleic acid comprising the genome of the herpesvirus of the invention, a vector comprising this nucleic acid and a cell comprising the nucleic acid or the vector. It further relates to killing cells using the herpesvirus of the invention and to methods for growing it in vitro. |
申请公布号 |
WO2016128497(A1) |
申请公布日期 |
2016.08.18 |
申请号 |
WO2016EP52879 |
申请日期 |
2016.02.11 |
申请人 |
ALMA MATER STUDIORUM UNIVERSITA' DI BOLOGNA |
发明人 |
CAMPADELLI, Maria Gabriella;GATTA, Valentina |
分类号 |
C12N7/00;A61K39/00;C12N5/10;C12N15/09;C12N15/62;C12N15/869 |
主分类号 |
C12N7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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