| 发明名称 |
A RHO GTPASE ACTIVATOR FOR USE AS ANTIMICROBIAL AGENT |
| 摘要 |
The invention relates to a Rho GTPase activator, such as namely the cytotoxic necrotizing factor 1 (CNF1), for use in preventing and/or treating infections by a pathogen in a patient in need thereof. The invention also relates to a Rho GTPase activator, such as CNF1, for use in preventing and/or treating pathologies associated with an infection by a pathogen in a patient in need thereof. For instance, the invention relates to a Rho GTPase activator for use in treating infections by bacteria in a patient in need thereof and also relates to a Rho GTPase activator for use in reducing or eliminating bacteremia in a patient in need thereof. |
| 申请公布号 |
US2016296595(A1) |
申请公布日期 |
2016.10.13 |
| 申请号 |
US201415036424 |
申请日期 |
2014.11.14 |
| 申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) ;UNIVERSITE NICE SOPHIA ANTIPOLIS ;CENTRE HOPITALIER UNIVERSITAIRE DE NICE |
发明人 |
LEMICHEZ Emmanuel;BOYER Laurent;DOYE Anne;MARTY Pierre;METTOUCHI Amel;MICHEL Gregory;MUNRO Patrick |
| 分类号 |
A61K38/16 |
主分类号 |
A61K38/16 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of preventing and/or treating pathogen infections and/or a pathology associated with a pathogen infection in a patient in need thereof, comprising
administering to the patient a therapeutically effective amount of a Rho GTPase activator. |
| 地址 |
Paris FR |
