发明名称 Ionizable cationic lipid for rna delivery
摘要 What is described is a compound of formula (1) wherein R1 and R2 are the same or different, each a linear or branched alkyl with 1-9 carbons, or an alkenyl or alkynyl with 2 to 11 carbon atoms; L1 and L2 are the same or different, each a linear alkyl having 5 to 18 carbon atoms, or form a heterocycle with N; X1 is a bond, or is —CO—O— whereby L2-CO—O—R2 is formed; X2 is S or O; L3 is a bond or a lower alkyl, or form a heterocycle with N; R3 is a lower alkyl; and R4 and R5 are the same or different, each a lower alkyl; or a pharmaceutically acceptable salt thereof.
申请公布号 IL245638(D0) 申请公布日期 2016.06.30
申请号 IL20160245638 申请日期 2016.05.15
申请人 ARCTURUS THERAPEUTICS INC. 发明人
分类号 C07C 主分类号 C07C
代理机构 代理人
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