发明名称 |
[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE DERIVATIVES AS PROTOZOAN PROTEASOME INHIBITORS FOR THE TREATMENT OF PARASITIC DISEASES SUCH AS LEISHMANIASIS |
摘要 |
The present invention provides compounds of Formula A: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a parasite, such as leishmaniasis, human African trypanosomiasis and Chagas disease. |
申请公布号 |
SG11201604618T(A) |
申请公布日期 |
2016.07.28 |
申请号 |
SGT11201604618 |
申请日期 |
2014.12.18 |
申请人 |
NOVARTIS AG |
发明人 |
BIGGART, AGNES;LIANG, FANG;MATHISON, CASEY JACOB NELSON;MOLTENI, VALENTINA;NAGLE, ADVAIT SURESH;SUPEK, FRANTISEK;YEH, VINCE |
分类号 |
C07D487/04;A61K31/519;A61P33/02 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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