TREATMENT OF PULMONARY ARTERIAL HYPERTENSION WITH PROSTACYCLIN TREATED ENDOTHELIAL PROGENITOR CELLS

摘要

The current application is directed to a method for treating pulmonary arterial hypertension (PAH) comprising: providing isolated endothelial progenitor cells (EPCs); treating the EPCs with prostacyclin wherein the treated EPCs exhibit a hyperproliferative phenotype with enhanced angiogenic property; and administering a composition comprising the treated EPCs into a subject suffering from PAH.