| 摘要 |
PROBLEM TO BE SOLVED: To provide a taste-masked microcapsule composition of a water-soluble drug, which can effectively mask the taste and immediately releases the drug, when passing through the mouth of a patient. SOLUTION: This taste-masked microcapsule composition of a water-soluble drug, the composition comprising microcapsules of the water-soluble drug (ranitidine such as H2 antagonist) in a polymeric material consisting essentially of one or more polymers selected from the group consisting of ethyl cellulose, cellulose acetate phthalate, cellulose acetate butyrate, polymethacrylates, hydroxypropyl methyl cellulose phthalate; carboxymethyl ethylcellulose; polylactic acid and combinations thereof, said polymeric material constituting approximately 30 wt.% to 65 wt.% of the composition. COPYRIGHT: (C)2006,JPO&NCIPI
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