| 发明名称 |
BIOACTIVE MODIFICATION OF POLY(VINYL ALCOHOL) WITH SURFACE TOPOGRAPHY AND BIOCHEMICAL CUES FOR VASCULAR GRAFT |
| 摘要 |
Modifications of the biomaterial poly(vinyl alcohol) with surface topographical cues, attachment factors for its improved performance, and/or sustained release of vascular endothelial biochemical cue for application as a vascular graft scaffold is described. Furthermore, novel fabrication methods to pattern the poly(vinyl alcohol) hydrogel in planar film or tubular form with the topographies in the lumen are disclosed. |
| 申请公布号 |
US2016361462(A1) |
申请公布日期 |
2016.12.15 |
| 申请号 |
US201615097749 |
申请日期 |
2016.04.13 |
| 申请人 |
NATIONAL UNIVERSITY OF SINGAPORE ;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
YIM King Fai Evelyn;LE VISAGE Catherine;CUTIONGCO Marie Francene Arnobit;TAN Ming Hao;GOH Seok Hong |
| 分类号 |
A61L27/16;A61L27/54;C08J7/12 |
主分类号 |
A61L27/16 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A bioactive scaffold, comprising:
poly(vinyl alcohol) scaffold and at least one modification at a surface of the scaffold, the at least one modification comprising a surface topographical cue and/or an attachment factor. |
| 地址 |
Singapore SG |
