发明名称 |
GRANULATE CONTAINING CANNABINOID METHOD FOR ITS MANUFACTURE AND ORAL DOSAGE UNIT COMPRISING SUCH GRANULATE |
摘要 |
The present invention relates to a granulate comprising granules made up of 40-99 wt.% of lactose particles and 1- 60 wt.% of a binding component that holds together the lactose particles within the granules. Said granules have a mass weighted average diameter of 50-500 µm and said binding component is a solid dispersion or a solid solution of 10-75 wt.% of a cannabinoid in 25-80 wt.% of a lipophilic matrix. The lipophilic matrix contains at least 80 wt.% sucrose fatty acid mono- ester, the fatty acid residue being selected from Cs-Cis fatty acids. The aforementioned granulate can be processed into oral dosage units in the form of tablets for oral delivery. The invention further provides a method for the manufacture of the granulate. |
申请公布号 |
IN9718DEN2014(A) |
申请公布日期 |
2015.07.31 |
申请号 |
IN2014DELNP9718 |
申请日期 |
2014.11.18 |
申请人 |
ECHO PHARMACEUTICALS B.V. |
发明人 |
DE VRIES ,JAN ALBERT;FERNANDEZ CID, MARIA VANESA;HEREDIA LOPEZ ,ANA MARIA |
分类号 |
A61K9/00;A61K9/16;A61K9/20 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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