| 发明名称 |
LABEL-FREE DETECTION OF MACROMOLECULES BINDING TO COMPOUND LIBRARIES |
| 摘要 |
A one-bead-one-compound (OBOC) assay technique and associated components and kits are disclosed herein. With the described assay, target macromolecules that are bound to compound beads, and the compounds can be identified and separated without labeling the compounds. |
| 申请公布号 |
US2016313311(A1) |
申请公布日期 |
2016.10.27 |
| 申请号 |
US201615136783 |
申请日期 |
2016.04.22 |
| 申请人 |
The Regents of the University of California |
发明人 |
Schlein Michael;Lam Kit S. |
| 分类号 |
G01N33/537;G01N27/447;G01N33/53 |
主分类号 |
G01N33/537 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of detecting a compound comprising:
contacting a compound bead library with one or more target macromolecules to form a compound-target macromolecule complex; combining the compound-target macromolecule complex with a separation matrix; separating the target macromolecules from the compound-target macromolecule complexes; staining separated target macromolecules; and isolating the compound. |
| 地址 |
Oakland CA US |
