METHOD & APPARATUS FOR CONTINUOUS AUTOMATED PERFUSION SYSTEM HARVESTING FROM IN-SITU FILTRATION PROBE

摘要

An apparatus and method for determining fluid flow (e.g., sterile media flow, filtrate flow, etc.) through tubing is provided. The apparatus includes an air source, a flow valve, a first sensor, a second sensor, and a media tubing section extending between the first sensor and the second sensor. In operation, air from the air source is introduced by the flow valve into a fluid flow to create a lead line of fluid immediately following the introduced air. As the lead line of fluid passes each sensor, the sensors are used to determine a time between when the lead line passes the first sensor and the second sensor and that determined elapsed time is used, along with a determined volume of the media tubing section to determine the rate of flow of the fluid flow.

主权项

1. A method for monitoring flow, the method comprising:
introducing an amount of air into a fluid flow; sensing, with a first sensor, a first time when a lead line of the fluid flow following the amount of air reaches the first sensor; sensing, with a second sensor, a second time when the lead line of the fluid flow reaches the second sensor; and using the first time and the second time to determine a flow rate for the fluid flow.