发明名称 COMBINATION THERAPY FOR TREATING VIRAL INFECTIONS
摘要 A method of treating viral infections, particularly Hepatitis B (HBV) and Human Immunodeficiency Virus (HIV) infections, by administering Elvucitabine and a second active agent to a patient suffering viral infection is provided herein. The second active agent is, for example, an immunomodulatory compound, an anti-viral agent, or a combination comprising one or more of the foregoing active agents. For example the anti-viral agent may be a tyrosine kinase inhibitor, a CCR5 inhibitor, a non-nucleoside reverse transcriptase inhibitor, a protease inhibitor, an integrase inhibitor. Further provided herein are combination dosage forms comprising Elvucitabine and a second active agent. The combination dosage may be administered once per day. The Elvucitabine may be administered less frequently than the second active agent. Packaged pharmaceutical compositions comprising Elvucitabine, a second active agent, and instructions for using the composition for treating a viral infection by administering Elvucitabine and the second active agent are also provided.
申请公布号 WO2006044968(A3) 申请公布日期 2006.06.15
申请号 WO2005US37597 申请日期 2005.10.18
申请人 ACHILLION PHARMACEUTICALS, INC.;POTTAGE, JOHN 发明人 POTTAGE, JOHN
分类号 A61K31/70;A61K31/535;A61K31/55;A61P31/14;A61P31/18 主分类号 A61K31/70
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