The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
申请公布号
WO2016149351(A1)
申请公布日期
2016.09.22
申请号
WO2016US22619
申请日期
2016.03.16
申请人
BRISTOL-MYERS SQUIBB COMPANY
发明人
BOY, Kenneth M.;SUN, Li-Qiang;ZHAO, Qian;MULL, Eric;GILLIS, Eric P.;SCOLA, Paul Michael
