发明名称 METHODS AND COMPOSITIONS FOR TREATING CANCER USING PEPTIDE NUCLEIC ACID-BASED AGENTS
摘要 The present invention provides compositions and methods for treating cancer with peptide nucleic acid agents. In some embodiments, the present invention provides methods and compositions relating to peptide nucleic acid agents that target oncogenes. For example, the present invention provides compositions, including pharmaceutical compositions, comprising agents specific for BRAF V600E inhibition, or fragments or characteristic portions thereof. The present invention further provides various therapeutic and/or diagnostic methods of using BRAF V600E specific peptide nucleic acid agents and/or compositions.
申请公布号 EP3087182(A2) 申请公布日期 2016.11.02
申请号 EP20140875786 申请日期 2014.12.17
申请人 MEMORIAL SLOAN KETTERING CANCER CENTER 发明人 ROTHMAN, JEFFREY K.;SCHWARTZ, GARY K.
分类号 C12N15/11;C07H21/04 主分类号 C12N15/11
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