Pharmaceutical preparation

摘要

A pharmaceutical preparation comprises nano-level particles (nanospheres) of a biocompatible polymer having, as held on their surfaces, an NFkappaB decoy capable of binding to NFkappaB to inhibit its activity. With penetration of the nanoparticles inside cells, the NFkappaB decoy may be delivered to an affected site and the NFkappaB decoy may be released from the surfaces of the nanoparticles and may be thereby efficiently and specifically introduced into the affected site.