发明名称 |
METHODS AND COMPOSITIONS FOR DIAGNOSING OR DETECTING LUNG CANCERS |
摘要 |
A multi-analyte composition for the diagnosis of lung cancer or lung disease comprises a ligand selected from a nucleic acid sequence, polynucleotide or oligonucleotide capable of specifically complexing with, hybridizing to, or identifying an mRNA gene transcript from a mammalian blood sample, and an additional ligand selected from a nucleic acid sequence, polynucleotide or oligonucleotide capable of specifically complexing with, hybridizing to, or identifying an miRNA of a gene from a mammalian blood sample. Each ligand and additional ligand binds to a different gene transcript or miRNA and the gene transcripts and miRNA identified form a characteristic profile of a stage of lung cancer or lung disease. Methods of using this composition for diagnosis and evaluation and methods for developing such compositions are described. |
申请公布号 |
WO2016187404(A1) |
申请公布日期 |
2016.11.24 |
申请号 |
WO2016US33232 |
申请日期 |
2016.05.19 |
申请人 |
THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY |
发明人 |
SHOWE, Louise, C.;SHOWE, Michael, K.;KOSSENKOV, Andrei, V. |
分类号 |
C40B30/04 |
主分类号 |
C40B30/04 |
代理机构 |
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地址 |
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