发明名称 |
Means and methods for treating peripheral and cardiovascular diseases via modulation of arteriogenesis |
摘要 |
<p>The present invention relates to a pharmaceutical composition comprising (a) a polynucleotide comprising or consisting of a nucleotide sequence encoding a polypeptide with the amino acid sequence as set forth in SEQ ID NO: 2; (b) a polynucleotide comprising or consisting of a nucleotide sequence which is a fragment of a nucleotide sequence encoding the polypeptide with the amino acid sequence as set forth in SEQ ID NO: 2, wherein the polypeptide encoded by said polynucleotide has arteriogenic activity; (c) a polynucleotide comprising or consisting of a nucleotide sequence encoding a polypeptide, wherein said polypeptide exhibits at least 70% sequence identity with the sequence of the polypeptide encoded by the polynucleotide of (a) or (b) over the entire length, and wherein said polypeptide has arteriogenic activity; and/or (d) a polypeptide encoded by the polynucleotide of any one of (a) to (c).</p> |
申请公布号 |
EP2030631(A1) |
申请公布日期 |
2009.03.04 |
申请号 |
EP20070017091 |
申请日期 |
2007.08.31 |
申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. |
发明人 |
SCHAPER, WOLFGANG;TROIDL, KERSTIN;TROIDL, CHRISTIAN;EITENMUELLER, INKA K. |
分类号 |
A61K48/00;A61K38/17 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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