发明名称 IMIDAZOLE DERIVATIVES AS CCR2 RECEPTOR ANTAGONISTS.
摘要 <p>The invention is concerned with novel imidazole derivatives of formula (I), wherein (Ia), m, E, R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup>, R<sup>4</sup>, R<sup>5</sup>, R<sup>6</sup> and R<sup>7</sup> are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR- 2 receptor, CCR-5 receptor and/or CCR-3 receptor and can be used as medicaments.</p>
申请公布号 MX2009014002(A) 申请公布日期 2010.01.28
申请号 MX20090014002 申请日期 2008.06.23
申请人 F. HOFFMAN-LA ROCHE AG 发明人 JOHANNES AEBI;ALFRED BINGGELI;PATRIZIO MATTEI;FABIENNE RICKLIN;OLIVIER ROCHE;LUKE GREEN;HANS P. MAERKI;GUIDO HARTMANN
分类号 C07D401/06;A61K31/4178;A61K31/4439;A61P9/00;C07D401/14;C07D403/06;C07D405/14 主分类号 C07D401/06
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