Devices for Estimating Regional Metabolic Rate of Organs Based on Heat Generation and for Estimating Regional Blood Flow(s) for the Volume(s) of Tissue Perfused

摘要

The present application provides systems that include a controller, and an insertion device with at least one temperatures sensor thereon and a pump coupled to the controller. The insertion device provides temperature measurement(s) at/of a subject's organ to the controller and the controller varies an infusate flow rate to induce temperature changes in at least a portion of the subject's organ and stores the temperature measurements during perfusion induced temperature changes on a memory device. The controller may estimate at least one hemodynamic characteristic of at least a portion of the subject's organ based on the temperature measurements obtained during perfusion induced temperature changes.

主权项

1. A system comprising:
a controller; an insertion device comprising at least one temperatures sensor thereon, the insertion device functionally coupled to the controller to provide at least one temperature measurement of a subject's organ to the controller; a pump functionally coupled to the controller for the controller to vary an infusate flow rate to induce temperature changes in at least a portion of the subject's organ; a memory device functionally coupled to the controller, the controller operable to store the at one measure of the temperature of an organ to the controller during perfusion induced temperature changes in at least a portion of the subject's organ, and further operable to estimate at least one hemodynamic characteristic of at least a portion of the subject's organ based on the at least one temperature measurement obtained during perfusion induced temperature changes.