发明名称 |
TREATMENT OF TUMOURS USING PEPTIDE-PROTEIN CONJUGATES |
摘要 |
Provided herein are methods for modulating tumour stroma, normalizing tumour vasculature and/or improving vascular function in a tumour, comprising exposing a tumour to an effective amount of a peptide-protein conjugate comprising a LIGHT polypeptide and a tumour homing peptide. Also provided are methods for treating tumours and increasing the survival time of tumour-bearing patients, comprising administering an effective amount of a peptide-protein conjugate comprising a LIGHT polypeptide and a tumour homing peptide. |
申请公布号 |
US2016206691(A1) |
申请公布日期 |
2016.07.21 |
申请号 |
US201514856238 |
申请日期 |
2015.09.16 |
申请人 |
The University of Western Australia |
发明人 |
Ganss Ruth;Johansson Anna |
分类号 |
A61K38/17;A61N5/10;A61K47/48 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
1. A method for treating a tumour in a subject, the method comprising administering to the subject an effective amount of a peptide-protein conjugate comprising a LIGHT polypeptide and a tumour homing peptide. |
地址 |
Crawley AU |