发明名称 PHARMACEUTICAL FOR PROPHYLAXIS OR TREATMENT OF HYPERTENSION
摘要 A pharmaceutical for the prophylaxis or treatment of hypertension or a disease derived from hypertension. The pharmaceutical is characterized by comprising (i) a specific mineralocorticoid receptor antagonist and (ii) one or more components selected from the following components (A) to (C), for administration simultaneously or separately at a time interval: (A) an angiotensin II receptor antagonist, (B) a calcium antagonist, and (C) a diuretic.
申请公布号 US2016206593(A1) 申请公布日期 2016.07.21
申请号 US201614996064 申请日期 2016.01.14
申请人 Daiichi Sankyo Company, Limited 发明人 Arai Kiyoshi;Homma Tsuyoshi;Mizuno Makoto
分类号 A61K31/40;A61K31/549;A61K31/4178;A61K31/4422 主分类号 A61K31/40
代理机构 代理人
主权项 1. A pharmaceutical for the prophylaxis or treatment of hypertension or a disease derived from hypertension, characterized by comprising (i) a mineralocorticoid receptor antagonist which comprises a substance selected from the group consisting of a compound represented by the following formula (I): and an atropisomer thereof, and a pharmacologically acceptable salt thereof, and (ii) one or more components selected from the following components (A) to (C), for administration simultaneously or separately at a time interval: (A) one or more angiotensin II receptor antagonists;(B) one or more calcium antagonists comprising a substance selected from the group consisting of a 1,4-dihydropyridine-based compound and a pharmacologically acceptable salt thereof; and(C) one or more diuretics.
地址 Tokyo JP