发明名称 |
SOLUBLE EPOXIDE HYDROLASE INHIBITORS |
摘要 |
Disclosed are urea and thiourea compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, and diabetic-related diseases. |
申请公布号 |
WO2008116145(A2) |
申请公布日期 |
2008.09.25 |
申请号 |
WO2008US57809 |
申请日期 |
2008.03.21 |
申请人 |
ARETE THERAPEUTICS, INC.;GLESS, RICHARD D., JR.;ANANDAN, SAMPATH KUMAR |
发明人 |
GLESS, RICHARD D., JR.;ANANDAN, SAMPATH KUMAR |
分类号 |
C07C275/24;A61K31/17;A61K31/5375;A61P3/10;A61P9/00;A61P9/12;A61P29/00;C07C275/30;C07C275/34;C07C275/36;C07D295/088;C07D413/12 |
主分类号 |
C07C275/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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