摘要 |
Provided are topical veterinary parasiticidal compositions comprising at least one isoxazoline active agent of general formula (I), wherein the variables are as defined in the specification. A preferred active agent is 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalanecarboxamide. The compositions also comprise a pharmaceutically acceptable carrier, one of the preferred carriers is a dialkyl ester of a C10-C22 dicarboxylic acid, such as diethyl sebacate, dibutyl sebacate or diisopropyl sebacate. |