<p>[PROBLEMS] To provide a method for obtaining an oligonucleotide, such as an RNA aptamer, having a high binding ability to a target substance in a simple manner and at high purity. [MEANS FOR SOLVING PROBLEMS] A method for obtaining an oligonucleotide, comprising the steps of: conducting the electrophoresis of a (nucleic acid molecule)/(target substance) complex composed of a nucleic acid molecule and a target substance; collecting the (nucleic acid molecule)/(target substance) complex; extracting the nucleic acid molecule from the (nucleic acid molecule)/(target substance) complex; and conducting the gene amplification of the nucleic acid molecule.</p>
申请公布号
WO2008015884(A1)
申请公布日期
2008.02.07
申请号
WO2007JP63741
申请日期
2007.07.10
申请人
NEC SOFT, LTD.;NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCEAND TECHNOLOGY;NISHIKAWA, FUMIKO;NISHIKAWA, SATOSHI;FURUICHI, MAKIO;MIZUNO, HIROSHI;WAGA, IWAO