ARYL AND HETEROARYL SUBSTITUTED ISOINDOLE DERIVATIVES AS BACE INHIBITORS
摘要
<p>This invention relates to novel compounds having the structural formula I below: (Formula I), and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.</p>
申请公布号
WO2009005471(A1)
申请公布日期
2009.01.08
申请号
WO2008SE50839
申请日期
2008.07.04
申请人
ASTRAZENECA AB;ASTEX THERAPEUTICS LTD;HOLENZ, JOERG;KERS, ANNIKA;KOLMODIN, KARIN;ROTTICCI, DIDIER;RAKOS, LASZLO;HELLBERG, SVEN
发明人
HOLENZ, JOERG;KERS, ANNIKA;KOLMODIN, KARIN;ROTTICCI, DIDIER;RAKOS, LASZLO;HELLBERG, SVEN