发明名称 |
Generation of heavy-chain only antibodies in transgenic animals |
摘要 |
The present invention relates to a method for the generation of VH heavy chain-only antibodies in a transgenic non-human mammal. In particular, the present invention relates to a method for the production of a VH heavy chain-only antibody in a transgenic non-human mammal comprising the step of expressing more than one heterologous VH heavy chain locus in that mammal. |
申请公布号 |
AU2007219159(A1) |
申请公布日期 |
2007.08.30 |
申请号 |
AU20070219159 |
申请日期 |
2007.01.25 |
申请人 |
ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM |
发明人 |
FRANKLIN GERARDUS GROSVELD;RICHARD WILHELM JANSSENS |
分类号 |
C07K16/00 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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