发明名称 QUINUCLIDINE DERIVATIVES AS MUSCARINIC M3 RECEPTOR ANTAGONISTS
摘要 The invention provides named compounds of formula (I), wherein R4 is a N- sustituted quinuclidine (I) pharmaceutical compositions containing them and a process for preparing the pharmaceutical compositions. Their use in therapy for' the treatment of conditions mediated by M3 muscarinic receptors, such as chronic obstructive pulmonary disease is also disclosed.
申请公布号 WO2009138707(A9) 申请公布日期 2010.01.28
申请号 WO2008GB01647 申请日期 2008.05.13
申请人 ASTRAZENECA AB;ARGENTA DISCOVERY LIMITED;FORD, RHONAN, LEE;MATHER, ANDREW, NIGEL;METE, ANTONIO;BULL, RICHARD, JAMES;SKIDMORE, ELIZABETH, ANNE 发明人 FORD, RHONAN, LEE;MATHER, ANDREW, NIGEL;METE, ANTONIO;BULL, RICHARD, JAMES;SKIDMORE, ELIZABETH, ANNE
分类号 C07D453/02;A61K31/439;A61P11/00 主分类号 C07D453/02
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