Fremstilling af 2-desoxynucleosider og 2-desoxynucleosidforstadier ud fra 2-dehydro-3-desoxy-D-gluconat

摘要

This invention relates to a process for preparing 2′-deoxynucleoside compounds or 2′-deoxynucleoside precursors using 2-dehydro-3-deoxy-D-gluconic acid (usually abbreviated as KDG) or its salts as a starting material. A variety of 2′-deoxynucleosides and their analogues are used as a starting material for synthesis or drug formulation in production of an antiviral, anticancer or antisense agent.