发明名称 |
2-morpholino-4-pyrimidone compound |
摘要 |
A compound represented by the formula (I), an optically active isomer thereof, or a pharmaceutical acceptable salt thereof:
wherein X represents CH or N; R 1 represents a C 1 -C 12 alkyl; R 2 represents a hydrogen atom, or the like; R' represents a C 1 -C 6 alkyl or the like; q represents 0 or an integer of 1 to 7; Y represents a C 1 -C 6 alkyl or the like; p represents 0 or an integer of 1 to 5; R represents a 2,3-dihydroindolyl or the like, which is used for preventive and/or therapeutic treatment of a disease caused by tau protein kinase 1 hyperactivity such as a neurodegenerative diseases (e.g. Alzheimer disease). |
申请公布号 |
ZA200702266(B) |
申请公布日期 |
2008.09.25 |
申请号 |
ZA20070002266 |
申请日期 |
2005.09.09 |
申请人 |
MITSUBISHI PHARMA CORPORATION;SANOFI-AVENTIS |
发明人 |
WATANABE, KAZUTOSHI;UEHARA, FUMIAKI;HIKI, SHINSUKE;KOHARA, TOSHIYUKI;FUKUNAGA, KENJI;YOKOSHIMA, SATOSHI |
分类号 |
A61K;A61P;C07D |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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