Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same
摘要
An improved method for the use of magnesium alkoxide for the preparation of starting materials and compounds for use herein is provided. The method is useful for preparing compounds of structure (5a)
having substituent groups as defined herein which compounds can be used in antiviral therapy and prophylaxis.
申请公布号
AU2001282941(C1)
申请公布日期
2016.12.22
申请号
AU20010282941
申请日期
2001.07.20
申请人
Gilead Sciences, Inc.
发明人
Becker, Mark W.;Chapman, Harlan H.;Cihlar, Tomas;Eisenberg, Eugene J.;He, Gong-Xin;Kernan, Michael R.;Lee, William A.;Prisbe, Ernest J.;Rohloff, John C;Sparacino, Mark L.