| 发明名称 |
COMPOSITIONS AND METHODS OF USING CHONDROITINASE ABCI MUTANTS |
| 摘要 |
The present invention relates to protein and nucleic acid mutants of chon droitinase ABCI. Such chondroitinase ABCI mutant enzymes exhibit altered cho ndroitin lyase activity or increased resistance to inactivation from stresso rs including UV light or heat. Methods of using chondroitinase ABCI mutant e nzymes are also provided. |
| 申请公布号 |
CA2666536(A1) |
申请公布日期 |
2008.04.17 |
| 申请号 |
CA20072666536 |
申请日期 |
2007.10.10 |
| 申请人 |
ACORDA THERAPEUTICS, INC. |
发明人 |
IACI, JENNIFER;VECCHIONE, ANDREA;CAGGIANO, ANTHONY O. |
| 分类号 |
C12N9/88;A61K38/51;A61P25/00;A61P25/04 |
主分类号 |
C12N9/88 |
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