| 发明名称 |
1-(4-PIPERIDINYL)-1,3-DIHYDRO-2H-BENZOXAZOLE-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS NOCICEPTIN ANALOGS AND OPIOID RECEPTOR LIKE RECEPTOR (ORL1) LIGANDS FOR THE TREATMENT OF PAIN |
| 摘要 |
<p>A compound of formula (II),
<Chemistry id="chema01" num="0001"><Image id="ia01" he="87" wi="48" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry>
wherein Z,A,B,R,R<Sub>1</Sub>,R<Sub>2</Sub>,Q and n are described herein.
It is an object of certain embodiments of the present invention to provide new compounds which exhibit affinity for the ORL1 receptor and one or more of the μ,δ or κ receptors for treating a patient suffering from chronic or acute pain.</p> |
| 申请公布号 |
EP1918279(A3) |
申请公布日期 |
2008.07.16 |
| 申请号 |
EP20080150838 |
申请日期 |
2002.04.18 |
| 申请人 |
EURO-CELTIQUE S.A. |
发明人 |
SUN, QUN;GOEHRING, RICHARD, R.;KYLE, DONALD;CHEN, ZHENGMING;VICTORY, SAM;WHITEHEAD, JOHN |
| 分类号 |
C07D211/04;A61K31/415;A61K31/4184;A61K31/44;A61K31/445;A61K31/454;A61K31/48;A61P3/04;A61P7/10;A61P9/00;A61P9/12;A61P11/06;A61P11/10;A61P11/14;A61P13/02;A61P21/02;A61P23/00;A61P25/00;A61P25/02;A61P25/04;A61P25/08;A61P25/14;A61P25/22;A61P25/28;A61P25/32;A61P25/36;A61P27/16;A61P29/00;A61P43/00;C07D209/34;C07D211/06;C07D235/24;C07D235/26;C07D263/58;C07D401/04;C07D401/06;C07D403/04;C07D403/06;C07D405/14;C07D413/04;C07D413/14;C07D471/04 |
主分类号 |
C07D211/04 |
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