发明名称 |
PROCESSES OF SYNTHESIZING DIHYDROPYRIDOPHTHALAZINONE DERIVATIVES |
摘要 |
Provided herein are processes for synthesizing dihydropyridophthalazinone derivatives, such as for example, 5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one and its stereoisomers, which are potent poly(ADP-ribose)polymerase (PARP) inhibitors as well as novel synthetic intermediate compounds. |
申请公布号 |
EP2533640(B1) |
申请公布日期 |
2016.09.28 |
申请号 |
EP20110740513 |
申请日期 |
2011.02.08 |
申请人 |
MEDIVATION TECHNOLOGIES, INC. |
发明人 |
WANG, BING;CHU, DANIEL;LIU, YONGBO;JIANG, QUAN;LU, LEI |
分类号 |
C07D471/06;C07D249/08;C07D401/04;C07D403/06;C07D405/06 |
主分类号 |
C07D471/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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