摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to polymorphous forms of deuterated omega-diphenylurea or salts thereof, particularly polymorphous forms of 4-(4-{3-[4-chloro-3-(trifluoromethyl)phenyl)-ureido]-phenoxy}-2-(N-1',1',1'-trideuterio-methyl)picolinamide of formula (I)or salt thereof.EFFECT: polymorphous forms are suitable for preparing a pharmaceutical composition used to inhibit phosphokinase (such as raf kinase).16 cl, 21 dwg, 10 ex |