发明名称 QUINAZOLINE INHIBITORS OF ACTIVATING MUTANT FORMS OF EPIDERMAL GROWTH FACTOR RECEPTOR
摘要 The invention relates to compounds of formula (I), or a pharmaceutically acceptable salt thereof:;;which possess inhibitory activity against activating mutant forms of EGFR, and are accordingly useful for their anti-cancer activity and in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of the compounds, or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.
申请公布号 US2016340342(A1) 申请公布日期 2016.11.24
申请号 US201615162816 申请日期 2016.05.24
申请人 AstraZeneca AB 发明人 LI David Yunzhi;WANG Jiabing;YANG Zhenfan;ZENG Qingbei;ZHANG Xiaolin
分类号 C07D403/12;A61K31/4985;A61K31/4184;A61K31/517;A61K39/395 主分类号 C07D403/12
代理机构 代理人
主权项 1. A compound of formula (I): or a pharmaceutically acceptable salt thereof.
地址 Sodertalje SE