发明名称 |
QUINAZOLINE INHIBITORS OF ACTIVATING MUTANT FORMS OF EPIDERMAL GROWTH FACTOR RECEPTOR |
摘要 |
The invention relates to compounds of formula (I), or a pharmaceutically acceptable salt thereof:;;which possess inhibitory activity against activating mutant forms of EGFR, and are accordingly useful for their anti-cancer activity and in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of the compounds, or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man. |
申请公布号 |
US2016340342(A1) |
申请公布日期 |
2016.11.24 |
申请号 |
US201615162816 |
申请日期 |
2016.05.24 |
申请人 |
AstraZeneca AB |
发明人 |
LI David Yunzhi;WANG Jiabing;YANG Zhenfan;ZENG Qingbei;ZHANG Xiaolin |
分类号 |
C07D403/12;A61K31/4985;A61K31/4184;A61K31/517;A61K39/395 |
主分类号 |
C07D403/12 |
代理机构 |
|
代理人 |
|
主权项 |
1. A compound of formula (I): or a pharmaceutically acceptable salt thereof. |
地址 |
Sodertalje SE |