发明名称 |
TRANSGENIC ANIMAL AS A MODEL FOR FIBROTIC DISEASES |
摘要 |
<p>A transgenic non-human animal with broad or cell type-specific ectopic expression offra-2 that manifests itself in a fibrotic disease, methods for obtaining such animal and their use. Fra-2 transgenic animals, in particular mice, are useful as model Systems for human fibrotic disease, e.g. lung scleroderma and pulmonary fibrosis. Cells obtained from the animal are useful for the analysis of fibrotic disease and for testing Compounds useful in the therapy of fibrotic disease.</p> |
申请公布号 |
WO2006089910(A1) |
申请公布日期 |
2006.08.31 |
申请号 |
WO2006EP60183 |
申请日期 |
2006.02.22 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;WAGNER, ERWIN;EFERL, ROBERT |
发明人 |
WAGNER, ERWIN;EFERL, ROBERT |
分类号 |
A01K67/027;C12N5/06 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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