摘要 |
<p>Compounds of formula (I) and isomers, salts, solvates, chemically protected forms, and prodrugs thereof one of X<SUP>1</SUP>, X<SUP>2</SUP> and X<SUP>3</SUP> is N, and the others are CH; R<SUP>N1</SUP> and R<SUP>N2</SUP> together with the nitrogen atom to which they are attached form a nitrogen-containing heterocyclic ring having from 4 to 8 ring atoms; R<SUP>N3</SUP> and R<SUP>N4</SUP> together with the nitrogen atom to which they are attached form a nitrogen-containing heterocyclic ring having from 4 to 8 ring atoms and their use in treating diseases ameliorated by the inhibition of mTOR.</p> |
申请人 |
KUDOS PHARMACEUTICALS LIMITED;HUMMERSONE, MARC GEOFFREY;GOMEZ, SYLVIE;MENEAR, KEITH ALLAN;COCKCROFT, XIAO-LING FAN;EDWARDS, PETER;LOH, VINCENT JUNIOR MING LAI;SMITH, GRAEME CAMERON MURRAY |
发明人 |
HUMMERSONE, MARC GEOFFREY;GOMEZ, SYLVIE;MENEAR, KEITH ALLAN;COCKCROFT, XIAO-LING FAN;EDWARDS, PETER;LOH, VINCENT JUNIOR MING LAI;SMITH, GRAEME CAMERON MURRAY |