发明名称 PYRAZOLE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS
摘要 The present invention relates to novel compounds of Formula (I), wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, M1, M2, M3, Am and Bn are defined as in Formula (I); invention compounds are modulators of metabotropic glutamate receptors - subtype 4 ("mGluR4") which are useful for the treatment or prevention of central nervous system disorders as well as other disorders modulated by mGluR4 receptors. The invention is also directed to pharmaceutical compositions and the use of such compounds in the manufacture of medicaments, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR4 is involved.
申请公布号 WO2009010455(A3) 申请公布日期 2009.03.05
申请号 WO2008EP59044 申请日期 2008.07.10
申请人 ADDEX PHARMA S.A.;BOLEA, CHRISTELLE;CELANIRE, SYLVAIN 发明人 BOLEA, CHRISTELLE;CELANIRE, SYLVAIN
分类号 C07D417/04;A61K31/4439;A61P27/02;C07D417/14 主分类号 C07D417/04
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