Deuterated analogs of pridopidine useful as dopaminergic stabilizers

摘要

Abstract The present invention provides novel deuterated analogs of Pridopidine, i.e. 4-(3 methanesulfonyl-phenyl)-1-propyl-piperidine. Pridopidine is a drug substance currently in clinical development for the treatment of Huntington's disease. In other aspects the invention relates to pharmaceutical compositions 10 comprising a deuterated analog of Pridopidine of the invention, and to therapeutic applications of these analogs.