发明名称 USE OF APTAMERS IN THERAPY AND/OR DIAGNOSIS OF AUTOIMMUNE DISEASES
摘要 The present invention is directed to an aptamer comprising or consisting of the nucleic acid sequence of SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 and/or a nucleic acid sequence being at least 80% identical to one of SEQ ID No. 1, 2 and 3 for use in therapy and/or diagnosis of autoimmune diseases, wherein the autoimmune disease is cardiomyopathy, dilated cardiomyopathy (DCM), peripartum cardiomyopathy (PPCM), idiopathic cardiomyopathy, Chagas' cardiomyopathy, Chagas' megacolon, Chagas' megaesophagus, Chagas' neuropathy, benign prostatic hyperplasia, scleroderma, psoriasis, Raynaud syndrome, pre-eclamsia, kidney allograft rejection, myocarditis, glaucoma, hypertension, pulmonary hypertension, malignant hypertension, and/or Alzheimer's disease.
申请公布号 US2016160218(A1) 申请公布日期 2016.06.09
申请号 US201514977780 申请日期 2015.12.22
申请人 Charité - Universitaetsmedizin Berlin ;Max-Delbrueck-Centrum fuer molekulare Medizin 发明人 Schimke Ingolf;Haberland Annekathrin;Wallukat Gerd
分类号 C12N15/115;G01N33/68;G01N33/564 主分类号 C12N15/115
代理机构 代理人
主权项
地址 Berlin DE