TTV MIRNA SEQUENCES AS AN EARLY MARKER FOR THE FUTURE DEVELOPMENT OF CANCER AND AS A TARGET FOR CANCER TREATMENT AND PREVENTION

摘要

Described are TTV miRNAs and probes and primers comprising part of said TTV miRNA polynucleic acid. The use of said compounds for diagnosis of cancer or predisposition of cancer is also described.

主权项

1. A TTV miRNA encoded by a torque teno virus (TTV) polynucleic acid comprising:
(a) a nucleotide sequence depicted in Table 1, 2a or 2b; (b) a nucleotide sequence having at least 60% identity to the nucleotide sequence of (a) and containing the nucleotide sequence CATCCYY (with Y: C or T); or (c) a fragment of the nucleotide sequence of (a) or (b) and containing the nucleotide sequence CATCCYY (with Y: C or T);